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Juvéderm is the only HA filler with FDA approval to last up to one year.* Ask your physician how you can get long-lasting results with Juvéderm®. Juvéderm® injectable gel is a next-generation smooth consistency gel dermal filler that helps to instantly restore your skin’s volume and smooth away facial wrinkles and folds like your œsmile lines or âœparentheses (nasolabial fold the creases that run from the bottom of your nose to the corners of your mouth). Juvéderm® comes in two formulations “Juvéderm® Ultra and Juvéderm® Ultra Plus.